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One-Pan Cheesy Tex-Mex John Wayne Casserole

Sally Thompson
This One-Pan Cheesy Tex-Mex John Wayne Casserole is the ultimate comfort food packed with bold Tex-Mex flavor, creamy layers, seasoned beef, and gooey melted cheese. Perfect for an easy dinner, quick family meal, potluck recipe, or cozy weeknight comfort food, this casserole combines a soft biscuit crust with rich taco-seasoned filling for a satisfying bite every time. If you’re searching for easy dinner ideas, cheesy casserole recipes, or simple one-pan meals the whole family will love, this hearty baked dish delivers incredible flavor with minimal cleanup.
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Prep Time 20 minutes
Cook Time 35 minutes
Total Time 55 minutes
Course Dinner
Cuisine Tex-Mex
Servings 6 servings
Calories 520 kcal

Ingredients
  

  • 1 pound ground beef
  • 1 tablespoon olive oil
  • 1 small onion diced
  • 1 green bell pepper diced
  • 2 cloves garlic minced
  • 1 packet taco seasoning
  • 1 can diced tomatoes drained
  • 1 small jalapeño diced
  • 1 can refrigerated biscuit dough
  • 8 ounces cream cheese softened
  • 1 cup sour cream
  • 2 cups shredded cheddar cheese
  • 1 cup shredded Monterey Jack cheese
  • 2 tablespoons chopped parsley or cilantro
  • 1 teaspoon salt
  • 1/2 teaspoon black pepper

Instructions
 

  • 1. Preheat the oven to 350°F and lightly grease a casserole dish or oven-safe skillet.
  • 2. Heat olive oil in a skillet over medium heat. Add ground beef and cook until browned while breaking it apart.
  • 3. Add diced onion, bell pepper, and garlic to the skillet. Cook until vegetables soften.
  • 4. Drain excess grease from the beef mixture.
  • 5. Stir taco seasoning, diced tomatoes, and jalapeños into the beef mixture and simmer for several minutes.
  • 6. In a separate bowl, mix softened cream cheese and sour cream until smooth.
  • 7. Press refrigerated biscuit dough evenly into the bottom of the prepared baking dish.
  • 8. Spread the beef mixture evenly over the biscuit layer.
  • 9. Carefully spread the cream cheese mixture over the meat layer.
  • 10. Sprinkle cheddar cheese and Monterey Jack cheese evenly over the top.
  • 11. Bake for 30 to 40 minutes until the cheese is bubbly and golden brown and the biscuit layer is fully cooked.
  • 12. Allow the casserole to rest for 5 to 10 minutes before slicing.
  • 13. Garnish with chopped parsley or cilantro before serving.

Notes

Softening the cream cheese before mixing creates a much smoother creamy layer.
Freshly shredded cheese melts better and creates a richer topping than pre-shredded cheese.
Allowing the casserole to rest before slicing helps the layers hold together perfectly.

Nutrition

Serving: 1servingCalories: 520kcalCarbohydrates: 28gProtein: 26gFat: 34gSaturated Fat: 16gPolyunsaturated Fat: 14gTrans Fat: 1gCholesterol: 95mgSodium: 980mgFiber: 2gSugar: 6g
Keyword beef casserole, casserole recipe, cheesy casserole, comfort food, easy casserole recipe, easy dinner, family dinner, one-pan meal, Tex-Mex casserole
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