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John Wayne Casserole

  • Author: Sally Thompson
  • Prep Time: 20 minutes
  • Cook Time: 35 minutes
  • Total Time: 55 minutes
  • Yield: 6 servings 1x
  • Category: Casserole
  • Method: Baking
  • Cuisine: Tex-Mex

Description

Hearty, cheesy, and packed with Tex-Mex flavor, this John Wayne Casserole is the ultimate comfort food perfect for weeknight dinners or crowd-pleasing gatherings. With seasoned ground beef, a creamy sour cream layer, and gooey cheddar cheese all baked over a fluffy biscuit base, this easy recipe is a satisfying meal in one dish. Ideal for those searching for quick dinner ideas, easy recipes, or family-friendly casseroles, this dish brings bold flavor with minimal effort — a must-add to your list of dinner ideas or meal prep favorites.


Ingredients

Scale

1 pound ground beef

1 packet taco seasoning

1 medium onion, chopped

1 can (10 oz) diced tomatoes with green chilies

1 cup corn (frozen or canned and drained)

1/2 cup sour cream

1/2 cup mayonnaise

2 cups shredded cheddar cheese

1 cup Bisquick or biscuit mix

1/2 cup milk

1 egg


Instructions

1. Preheat oven to 350°F (175°C).

2. In a bowl, mix biscuit mix, milk, and egg until just combined. Spread in a greased 9×13-inch baking dish.

3. In a skillet over medium heat, cook ground beef until browned. Add onion and cook until softened.

4. Stir in taco seasoning, diced tomatoes with green chilies, and corn. Simmer for 5 minutes.

5. Spread the beef mixture over the biscuit base.

6. In another bowl, mix sour cream and mayonnaise. Spread this over the beef layer.

7. Sprinkle cheddar cheese evenly on top.

8. Bake for 30–35 minutes until bubbly and golden. Let rest for 5–10 minutes before serving.


Notes

Use room-temperature sour cream and mayonnaise for easier spreading.

Drain canned ingredients well to avoid excess moisture.

Let the casserole rest before slicing to help it hold its shape.


Nutrition

  • Serving Size: 1 slice
  • Calories: 420
  • Sugar: 4g
  • Sodium: 680mg
  • Fat: 28g
  • Saturated Fat: 12g
  • Unsaturated Fat: 13g
  • Trans Fat: 0g
  • Carbohydrates: 22g
  • Fiber: 2g
  • Protein: 23g
  • Cholesterol: 95mg

Keywords: easy recipe, dinner ideas, quick dinner, john wayne casserole, casserole recipe, tex-mex casserole